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Synopsis HIV-infected older individuals are at increased risk of developing cerebral small vessel disease (CSVD). Quantitative susceptibility mapping (QSM) can be used to asses tissue susceptibility, which can be a measure of CSVD. CSVD tends to occur more frequently in HIV-positive individuals. Limited information in the literature is available on HIV-associated changes in brain tissue … Continue reading HIV-Associated Cerebral Small Vessel Disease as Measured by Quantitative Susceptibility Mapping – ISMRM 2019 Poster Session
Introduction Diffusion MRI (dMRI) signal can be reconstructed by fitting various signal models that reflect different aspects of white matter structure. Three of these models are diffusion tensor imaging (DTI),1 diffusion kurtosis imaging (DKI),2 and neurite orientation dispersion and distribution index (NODDI).3 DTI can be used to calculate fractional anisotropy (FA) and mean, axial, and radial diffusivities (MD, … Continue reading Tract-Based Spatial Statistics of Cerebral Small Vessel Disease in an HIV Population – OHBM 2020 Poster Session
Synopsis The integration of structural and functional connectivity thus far has been limited to atlas-based parcellation studies. We present a novel atlas-free processing pipeline to explore the integration of structural and functional connectivity at high spatial resolution. This pipeline has been reliably replicated in other research subjects. We also introduce a dual-modality imaging feature that … Continue reading Surface-Based Connectivity Integration: A Processing Pipeline for High Resolution Integration of Structural and Functional Connectivity – ISMRM 2020 Poster Session
Synopsis HIV-infected individuals are at increased risk of developing white matter hyperintensities (WMHs), which can lead to increased iron deposition in deep gray matter structures. In this abstract, we evaluate three region of interest (ROI) brain iron metrics and introduce a novel population-based whole-brain iron metric, the expected iron coefficient (EIC), derived from quantitative susceptibility … Continue reading Brain Iron Imaging Markers in the Presence of White Matter Hyperintensities – ISMRM 2020 Poster Session